Humanity reached the stars, colonizing planets deep in the galaxy. But a century later, the T'Akons, a powerful alien race appeared. The machine-based aliens conquered the colonies with their advanced technology. They also began their quest to remake humans into their own cybernetic likeness. On the planet Zanath, the aliens create cybernetic-hybrid humans that now comprise a majority of the population. Unmodified humans are shunned on Zanath and forced to live in ghettos. One such human is Kira Zo, a soldier. She is smart, beautiful and headstrong. Her parents, against the wishes of the government, bear another unmodified child. The enraged T'Akons kill the infant and her parents. Vowing revenge for the death of her family, Kira organizes a Resistance movement. The group is an uneasy alliance of defiant humans and hybrid defectors. She also seeks the support of the Elayans, an alien race from the other side of the galaxy and mortal enemies of the T'Akons. But the T'Akons crush the Resistance, and Kira and what's left of her group flee Zanath. They continue the rebellion on Earth, which is now a technologically backward planet left in ruins by nuclear war.
As Kira races to form the alliance with the Elayans, while trying to keep her infighting group together, the T'Akons find and imprison her. She escapes and finally enlists the Elayans. With their help, she mounts a climactic series of battles that will determine the future of humanity.